![]() Drugs that might be co-administered with etorphine could then be tested for their ability to mitigate the hypoxemia first in captivity and then in the field. Observing the effects of etorphine on pulmonary blood pressure and flow in white rhinoceros habituated to captivity in bomas without the confounding effects of exertion or other drugs would help determine some of the mechanisms responsible for hypoxemia in these animals. In other species given etorphine, hypoxemia has been attributed to pulmonary hypertension. Hypoxemia may result in morbidity and mortality. ![]() The hypoxemia is likely due to the adverse cardiopulmonary effects of the potent opioid used for immobilization, etorphine, combined with extreme exertion during capture in the field. Management of wild rhinoceros requires capture by chemical immobilization unfortunately, this induces profound physiological derangements, including severe hypoxemia. White rhinoceros (Ceratotherium simum) are classified as “near-threatened” due to poaching and must be managed actively to ensure their conservation. Meyer, BSc Hon, BVSc, PhD, Associate Professor Veterinary Pharmacology, Department of Paraclinical Sciences, University of Pretoria, South Africa Gleed, BVSc, MA, MRCVS, DVA, DACVAA, DECVAA, MRCA, Professor of Clinical Sciences, Department of Clinical Sciences Mitigating the Adverse Effects of Etorphine-based Capture in White Rhinoceros
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